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Tag: Bioreactor

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    Addressing scaling challenges of bioreactor sparging using mass flow control

    Addressing scaling challenges of bioreactor sparging using mass flow control This article was originally published in Fluid Handling Pro on June 29, 2021. Read the original article here. Bioreactor sparging systems are designed to introduce oxygen to feed cell cultures, while removing carbon dioxide to prevent toxic buildup. Various bioreactor features and components are critical to […]

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    Inflating single-use bioreactor bags using dual-valve pressure controllers

    Inflating single-use bioreactor bags using dual-valve pressure controllers Single-use bioreactors (SUBs) offer key advantages over reusable bioreactors, including increased sterility and subsequently simpler and faster changeover between batches or campaigns. After the product is removed from the bioreactor, the user can remove the SUB bag from its holding container and dispose of it (generally via […]

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    Alicat mass flow controllers resist back pressure contamination

    Evaluation of Alicat mass flow controllers’ resistance to back pressure contamination Mass flow controllers (MFCs) are essential to many modern production and test processes. Precise and reliable flow control is particularly important for efficient, sustainable production in applications such as glass fabrication and bioprocessing. Within such processes, MFCs occasionally face the challenge of encountering unexpected […]

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    Accurate and simplified pressure decay leak testing for single-use bioprocessing

    How do you know that your bioprocessing is free from costly leaks or integrity failures? Leak testing of single use systems can now be accomplished easily and quickly with an Alicat Scientific Whisper Series Mass Flow Meter.

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    More efficient flow control for bioreactors and bioprocess systems

    More efficient flow control for bioreactors and bioprocess systems Cowritten by Alicat and Chip Stacy, AbbVie Senior Engineer of Digital Systems As the need for potent and specific pharmaceuticals grows, pharmaceutical manufacturers have turned to biologics to meet the increasing needs and find treatments for complex and currently untreatable conditions including cancer and myriad genetic […]

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    High flow control for gasification

    High flow control for gasification Gasification is a process in which biomass or fossil fuel is converted into carbon monoxide, hydrogen, and carbon dioxide (syngas or synthetic gas).1 According to Carnot’s theorem of thermodynamic efficiency, the syngas produced is more energy rich than organic fuel in its combustion due to higher combustion temperatures. Furthermore, syngas […]

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    Lowering cost and increasing speed of biologics production

    Lowering cost and increasing speed of biologics production With protocols for bioprocessing firmly established, there is an increasing focus on reducing the cost of producing biologics, biosimilars, mABs, and other modern medicines requiring bioreactions. Producing these pharmaceuticals promises to revolutionize treatment of many difficult diseases, especially modern scourges that have been resistant to small molecule-based […]

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    ILS Automation integrates mass flow control with industrial communication protocols into bioreactors

    ILS Automation integrates mass flow control with industrial communication protocols into bioreactors Many pharmaceutical and agricultural products, biofuels, and biochemicals are produced in a fermentation process similar to the way beer is made. Biotech and chemical research companies that make such products need to accurately control the amount of each gas that is fed into […]