Bioprocessing & Bioreactors

Proven Mass Flow Performance for Bioprocess & Bioreactor Applications

Our BIO Series provides unmatched reliability, extreme flexibility and precise measurements in the world’s only bioreactor mass flow controller. Experience the Alicat difference – where modern design and solid state construction provide solutions for bioreactor mass flow control.

  • Fermenters
  • Bioreactors and bioprocess applications
  • Biologics production
  • Biosimilar development
  • Biofuel production
  • Nuticeutical development

Reliable, Adaptable and Compatible Flow Control

BIO-Series Precision Flow Control for Bioreactors
Flexible configuration, customized for your needs. Everything you need, nothing you don’t.

The fastest way to enhance your bioreactor mass flow controller systems.

  • Built with your preferred industrial protocols and Pharma 4.0 in mind
  • FDA-grade elastomers prevent contamination
  • Backflow tolerance with zero calibration drift
  • Gas Select feature enables exchange of controller gasses without re-calibration or loss of accuracy
  • 316L stainless steel for durability and stability, with a lifetime warranty
  • Wide range flow rates and compatibility with multiple gasses eliminates unnecessary piping

Elastomer Concerns for Bioreactors

Fermenters and bioreactors require very low outgassing from wetted materials, in order to ensure that resulting products and free from unwanted contaminants.  Many elastomers can meet the requirements set out by the ASME BPE-2016 guidelines – but which ones are right for your bioprocess control? Choosing an Alicat BIO Series Mass Flow Controller will ensure that your bioreactor receives the precise amount of gas your system needs – with no unwanted contamination.

Alicat Elastomer gasket for BIO Series mass flow controllers for bioprocessing
Bio series gas flow controller for bioprocessing

Optimizing Bioreactor Production

Bioreactors are used for producing biologics, biosimilars, fertilizers and pesticides, brewing beer, refining ethanol, and treating wastewater. Make existing systems ready for Pharma 4.0 by replacing rotameters with bioreactor mass flow controllers.

High Flow Control for Gasification

Alicat Scientific Mass Flow Controllers can be used in multiple areas of the gasification process: combustion, clean-up bioreactors, safety, & quality control. Get more precise syngas production, redundancy between units and extremely fast control. Alicat’s MCR controllers with near-frictionless Rolamite proportional control valves- rapidly & precisely control flow rates up to 5000 SLPM.

Biomass Plant in Germany
mfc bioprocessing flow control

Reduced Costs with 0.1% of Full Scale Accuracy

There is an increasing focus on reducing the cost of producing biologics, biosimilars, mABs and other modern medicines. Whether using stainless steel tank or single use bioreactors, you can reduce your cost per run by replacing rotameters. Alicat’s accuracy – as low as .1% of full scale and repeatability of +/- .02% of full scale readings – makes this possible. Improve your bioprocess control and fermenter production.

Mass Flow Considerations for Wastewater Treatment

Improvements of water quality and efficiency of treatment can be improved with the latest bioprocess controls and bioreactors.  Pressure control can also play a role in helping obtain maximum efficiency. Whether using corrosion resistant mass flow controllers or high accuracy smart pressure controllers, Alicat has a solution to improve your wastewater bioreactor controls.

Water being filled into treatment tank for hydrotesting
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