Bioprocessing & Bioreactors

Proven Mass Flow Performance for Bioprocess & Bioreactor Applications

Experience the Alicat difference – where modern design and solid state construction provide solutions for bioreactor mass flow control. Including: fermenters, many types of bioreactors and bioprocess applications; biologics production, biosimilar development, biofuel production, nuticeutical development and much, much more. Our New BIO-Series provides unmatched reliability, extreme flexibility and precise measurements in the world’s only bioreactor mass flow controller.

Reliable, Adaptable and Compatible Flow Control

BIO-Series Precision Flow Control for Bioreactors
Flexible configuration, customized for your needs. Everything you need, nothing you don’t.

The fastest way to enhance your bioreactor mass flow controller systems

  • Built with your preferred industrial protocols and Pharma 4.0 in mind
  • FDA-grade elastomers prevent contamination
  • Backflow tolerance with zero calibration drift
  • Gas Select feature enables exchange of controller gasses without re-calibration or loss of accuracy
  • 316L stainless steel for durability and stability, with a lifetime warranty
  • Wide range flow rates and compatibility with multiple gasses eliminates unnecessary piping

Elastomer Concerns for Bioreactors

Fermenters and bioreactors require very low outgassing from wetted materials, in order to ensure that resulting products and free from unwanted contaminants.  Many elastomers can meet the requirements set out by the ASME BPE-2016 guidelines – but which ones are right for your bioprocess control? Choosing an Alicat BIO Series Mass Flow Controller will ensure that your bioreactor receives the precise amount of gas your system needs – with no unwanted contamination.

Optimizing Bioreactor Production

Bioreactors are used in a growing number of applications, from producing biologics, biosimilars and environmentally friendly fertilizers and pesticides, to brewing beer, refining ethanol and treating wastewater. The increase in bioprocess control requirements and single use reactors has led to a need for even greater precision and flexibility in instrumentation. Make existing systems ready for Pharma 4.0 by replacing bioprocess rotameters with bioreactor mass flow controllers.

Alicat Scientific’s broad range of mass flow controllers simplifies and streamlines your bioreactor development lifecycle.

High Flow Control for Gasification

Alicat Scientific Mass Flow Controllers can be used in multiple areas of the gasification process: combustion, clean-up bioreactors, safety, & quality control. Get more precise syngas production, redundancy between units and extremely fast control. Alicat’s MCR controllers with near-frictionless Rolamite proportional control valves- rapidly & precisely control flow rates up to 5000 SLPM. With accuracy of +/- (0.8% of reading + 0.2% of full scale range) to high flow rates, precise composition can be ensured and improved flow control achieved.

Reduced Costs with 0.1% of Full Scale Accuracy

With protocols for bioprocessing now firmly established, there is an increasing focus on reducing the cost of producing biologics, biosimilars, mABs and other modern medicines. Whether using stainless steel tank or single use bioreactors, you can reduce your cost per run, by replacing outdated rotameters. Alicat’s astonishing mass flow accuracy –  as low as .1% of full scale and unbeatable repeatability of +/- .02% of full scale readings – helps make this possible. Improve your bioprocess control and fermenter production.

Mass Flow Considerations for Wastewater Treatment

Improvements of water quality and efficiency of treatment can be improved with the latest bioprocess controls and bioreactors.  Pressure control can also play a role in helping obtain maximum efficiency. Whether using corrosion resistant mass flow controllers or high accuracy smart pressure controllers, Alicat has a solution to improve your wastewater bioreactor controls.


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