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Tag: controller

  • Addressing scaling challenges of bioreactor sparging using mass flow control

    This article was originally published in Fluid Handling Pro on June 29, 2021. Read the original article here. Bioreactor sparging systems are designed to introduce oxygen to feed cell cultures while removing carbon dioxide to prevent toxic buildup. Various bioreactor features and components are critical to optimizing these processes. Spargers, impellers, baffling, and bioreactor shape all […]

  • High accuracy, low-flow color dosing with Coriolis mass flow meters

    Many liquid laundry detergents are easily recognized by their distinct blue color. The addition of such blue coloring and other fluorescing agents adds trace amounts of dye to fabrics, both counteracting discoloration and improving brightness. Challenge: Inaccurate, inefficient pumps lead to noticeable variation Modern blue dyes and fluorescing agents come in extremely high concentrations, so […]

  • Alicat mass flow controllers resist back pressure contamination

    Evaluation of Alicat mass flow controllers’ resistance to back pressure contamination Mass flow controllers (MFCs) are essential to many modern production and test processes. Precise and reliable flow control is particularly important for efficient, sustainable production in applications such as glass fabrication and bioprocessing. Within such processes, MFCs occasionally face the challenge of encountering unexpected […]

  • More efficient flow control for bioreactors and bioprocess systems

    Cowritten by Alicat and Chip Stacy, AbbVie Senior Engineer of Digital Systems As the need for potent and specific pharmaceuticals grows, pharmaceutical manufacturers have turned to biologics to meet the increasing needs and find treatments for complex and currently untreatable conditions including cancer and myriad genetic diseases. Biologics and biosimilars differ from conventional small molecule drugs […]

  • Inchfab uses mass flow and pressure control in nanoscale fabrication systems

    Cowritten by Alicat; Mitchell Hsing, Ph.D., CEO & Co-Founder of Inchfab; and Parker Gould, Ph.D., CTO & Co-Founder of Inchfab Background: Nanoscale fabrication systems & Inchfab The increasing demand for computing power over the past 60+ years has led to exponential increases in both device complexity and production volumes. To keep up with this demand, […]

  • Maintaining cryogenic temperatures with pressure control

    Cryogens are substances that liquefy at or below 120 K under standard pressure (760 Torr). They are commonly used in applications to keep liquefied substances at extremely cold temperatures, including cryopreservation, rocket propulsion, and medical imaging. Two of the most well-know cryogens are liquid nitrogen and helium. Liquid nitrogen is commonly used for cold storage […]

  • Biosphere 2 studies the impacts of drought on tropical rainforests using flow measurement

    As the Earth’s climate changes, scientists expect that a hotter, drier world will have severe impacts on global ecosystems, with many areas subjected to increased water stress and/or drought. However, it is difficult to forecast the specific impact climate change will have on soil, air, and water quality across different regions of the world. In […]

  • Aerating chocolate using mass flow control

    Aerated chocolate is increasingly popular because of its particular mouthfeel: bubbles in the chocolate make it lighter, with a unique texture. An aerated chocolate bar has more surface area than a standard chocolate bar, which is why it melts faster in your mouth, intensifying its taste. How are bubbles added to chocolate? The short answer: […]

  • Controlling carbon dioxide sparging in brewing applications

    Beer is the beverage of choice for billions of people around the world. Whether ale, lager, or stout, carbon dioxide sparging is the process by which beer gets carbonated – making it the not-so-subtle difference between a refreshing pint and a flat disappointment. The average beer drinker is like to have strong feelings about what […]

  • Veloce echelle spectrograph utilizes closed-volume pressure control

    Dr. James Gilbert Dr. James Gilbert was the technical lead for the Australian National University’s development of the Veloce echelle spectrograph, which is now installed on the 3.9-meter Anglo-Australian Telescope at the Siding Spring Observatory in New South Wales, Australia. Veloce integrates a highly-customized Alicat closed-volume pressure controller for stable precision pressure control of air […]

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