Bioprocessing has very specific requirements for wetted materials, in order to avoid contamination of the bioreactor environment. The main potential contaminants are materials outgassed from elastomers, typically adsorbed onto elastomers during polymerization. While mass flow meters typically lie outside of the sterile boundary, and should not have contact with the final product, it is still good practice to follow the BPE-2016 standards. To avoid the impacts of outgassing, Alicat uses only USP Class VI elastomers with good permeation resistance. Additionally, elastomers used should be FDA certified. All of Alicat’s units use corrosion resistant elastomers recommended by the BPE-2016 standards. While several types of elastomer are available, Viton brand FKM (Fluoroelastomer ASTM D1418) meets the BPE 2016 standards, as well as being available in USP Class VI FDA certified form. Viton branded FKM also carries the implicit guarantee of Dupont’s high quality manufacturing standards. Alicat understands the importance of choosing a mass flow meter which meets these requirements– and helps avoid potential contaminations of bioprocesses.