{"id":38362,"date":"2024-03-26T16:48:14","date_gmt":"2024-03-26T16:48:14","guid":{"rendered":"https:\/\/www.alicat.com\/?post_type=article&#038;p=38362"},"modified":"2026-01-26T16:29:14","modified_gmt":"2026-01-26T16:29:14","slug":"penn-electronic-design-shop-an-der-universitat-von-pennsylvania-nutzt-mass-flow-control-zur-optimierung-von-olfaktometern-fur-die-forschung-zum-kurzzeitgedachtnis","status":"publish","type":"support","link":"https:\/\/www.alicat.com\/de\/support\/penn-electronic-design-shop-at-the-university-of-pennsylvania-uses-mass-flow-control-to-optimize-olfactometer-for-short-term-memory-retention-research\/","title":{"rendered":"Penn Electronic Design Shop optimiert Olfaktometer f\u00fcr die Erforschung des Kurzzeitged\u00e4chtnisses mit Hilfe von Massenflussregelung"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_row _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_heading title=&#8221;Penn Electronic Design Shop uses mass flow control to optimize olfactometer for short-term memory retention research&#8221; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]Advances in science have resulted in a much deeper understanding of the most complex organ in the human body: the brain. One remaining mystery is the mechanism by which a human brain retains and recalls information. The Gottfried lab at the University of Pennsylvania is working hard to solve this mystery through the study of olfaction (the sense of smell).\n\nTheir work on olfaction could yield exciting results on the link between short-term memory retention and the brain activity by which it is facilitated.\n<h2>The experiment<\/h2>\nThe lab designed an experiment to gain insight into the correlation between scent, short-term memory retention, and brain activity. Here is a brief overview of the experimental process:\n<ol>\n\t<li>Set up an MRI machine to monitor the brain activity of subjects.<\/li>\n\t<li>Present subjects with a series of three distinct scents.<\/li>\n\t<li>Wait for a short period of time, varying from 7 to 10 seconds<\/li>\n\t<li>Introduce subjects to an additional scent.<\/li>\n\t<li>Subjects then determine if the scent was one of the three above, and in which order they think they initially smelled it.<\/li>\n<\/ol>\nTo facilitate this research, the lab needed a machine to precisely dispense specific volumes of each scent. That\u2019s where Miguel Hernandez, director of the Penn Electronic Design Shop and his team, came in.\n<h2>Challenge 1: Building an olfactometer to precisely deliver scents<\/h2>\nTo conduct this experiment, the lab endeavored to develop an olfactometer capable of precisely delivering up to 12 different scents using pneumatics and air pressure. The first iteration of this machine was unable to operate with high enough precision due to valve limitations.\n\nIn the Penn Electronic Design Shop, the team improved the electrical design of the olfactometer and streamlined the device. The final version utilizes two <a href=\"https:\/\/www.alicat.com\/products\/gas-flow\/mass-flow-controller\/laminar-dp-mass-flow-controllers\/\">Alicat mass flow controllers<\/a> (MC-20SLPM) to regulate the flow of oxygen through each scent container at established intervals. According to Mr. Hernandez, \u201cthere is confidence that the Alicat flow controllers and their measurements will be precise.\u201d\n<h2>Challenge 2: Interfacing the controllers and solenoid valves at each scent container<\/h2>\nThe next challenge was interfacing the mass flow controllers and the solenoid valves at each scent container. After discussing the situation with Alicat\u2019s engineering team, Mr. Hernandez tested the analog electronic design and used MatLab software to provide commands to control system. A MatLab open-source software package called PsychToolbox enabled him to create a streamlined command interface, making it easy to adjust the flow controllers and regulate the saturation of oxygen flowing to any given valve.\n\nThe real-time parameters displayed on the Alicat controllers\u2019 <a href=\"https:\/\/www.alicat.com\/support\/digital-displays\/\">integrated displays<\/a> also made it easy for Mr. Hernandez to monitor process outputs and ensure the olfactometer\u2019s electronics were functioning properly.\n\n&nbsp;[\/et_pb_text][et_pb_image src=&#8221;https:\/\/www.alicat.com\/wp-content\/uploads\/2024\/04\/Olfactometer-System.webp&#8221; title_text=&#8221;Olfactometer-System&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;20px||5px||false|false&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<h6 style=\"text-align: center;\">Olfactometer system<\/h6>\n<h2><\/h2>\n<h2><strong>Conclusions<\/strong><\/h2>\n<p>After final testing of the olfactometer, Mr. Hernandez delivered a compact and precise device to the Gottfried lab, tailored exactly to their research parameters. The lab has since used the machine in a variety of research projects, and has found that subjects\u2019 brain activity independently codes for the \u201cwhat\u201d of the scent and the \u201cwhen\u201d of the odor sequences.<\/p>\n<p>The team observed that the delay in activity had a direct effect on the later recall of the scent. The results also indicate that certain patterns of brain activity enable multiple memory items that share a common \u201clocation\u201d in the brain to be independently maintained, allowing for separate recall.<\/p>\n<h2><\/h2>\n<h2>What is next for the Gottfried lab?<\/h2>\n<p>While this project does answer some questions surrounding short-term memory retention and how the brain functions during recall, there is still a lot more work for the Gottfried lab. The team intends to continue using Mr. Hernandez\u2019s olfactometer to learn more about retention and recall of information in the brain.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"featured_media":46458,"parent":0,"template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"1920","content-type":"","_searchwp_excluded":""},"categories":[],"class_list":["post-38362","support","type-support","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Penn Electronic Design Shop Uses Mass Flow Control to Optimize Olfactometer for Short-Term Memory Retention Research - Alicat Scientific<\/title>\n<meta name=\"description\" content=\"Learn how Alicat devices are used by Penn Electronic Design Shop to optimize olfactometers for short-term memory retention research\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.alicat.com\/de\/unterstutzung\/penn-electronic-design-shop-an-der-universitat-von-pennsylvania-nutzt-mass-flow-control-zur-optimierung-von-olfaktometern-fur-die-forschung-zum-kurzzeitgedachtnis\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Penn Electronic Design Shop Uses Mass Flow Control to Optimize Olfactometer for Short-Term Memory Retention Research\" \/>\n<meta property=\"og:description\" content=\"Learn how Alicat devices are used by Penn Electronic Design Shop to optimize olfactometers for short-term memory retention research\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.alicat.com\/de\/unterstutzung\/penn-electronic-design-shop-an-der-universitat-von-pennsylvania-nutzt-mass-flow-control-zur-optimierung-von-olfaktometern-fur-die-forschung-zum-kurzzeitgedachtnis\/\" \/>\n<meta property=\"og:site_name\" content=\"Alicat Scientific\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/alicatscientific\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-26T16:29:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.alicat.com\/wp-content\/uploads\/2026\/01\/featured-alicat.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.alicat.com\\\/support\\\/penn-electronic-design-shop-at-the-university-of-pennsylvania-uses-mass-flow-control-to-optimize-olfactometer-for-short-term-memory-retention-research\\\/\",\"url\":\"https:\\\/\\\/www.alicat.com\\\/support\\\/penn-electronic-design-shop-at-the-university-of-pennsylvania-uses-mass-flow-control-to-optimize-olfactometer-for-short-term-memory-retention-research\\\/\",\"name\":\"Penn Electronic Design Shop Uses Mass Flow Control to Optimize Olfactometer for Short-Term Memory Retention Research - 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