{"id":38083,"date":"2024-02-06T00:08:28","date_gmt":"2024-02-06T00:08:28","guid":{"rendered":"https:\/\/www.alicat.com\/?post_type=article&#038;p=38083"},"modified":"2026-02-16T20:55:53","modified_gmt":"2026-02-16T20:55:53","slug":"uberprufung-und-optimierung-von-gaschromatographieprozessen","status":"publish","type":"support","link":"https:\/\/www.alicat.com\/de\/support\/verifying-and-optimizing-gas-chromatography-processes\/","title":{"rendered":"\u00dcberpr\u00fcfung und Optimierung von Gaschromatographie-Prozessen"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|0px|3px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_row _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;3px|||||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<div id=\"eckb-article-content-header\">\n<h1 class=\"eckb-article-title\"><strong>Verifying and optimizing gas chromatography processes<\/strong><\/h1>\n<div class=\"eckb-article-content-header__article-meta\"><\/div>\n<\/div>\n<div id=\"eckb-article-content-body\">\n<p>Gas chromatography (GC) is an important analytical technique used to separate and analyze chemical components in a mixture. Here, we provide a brief introduction to GC and discuss some of the common application challenges and mass flow\/pressure solutions.<\/p>\n<h2><\/h2>\n<h2>How does gas chromatography work?<\/h2>\n<p>The sample is first injected into the inlet of the GC, where a steady flow of an inert \u201ccarrier gas\u201d is used to move it through a packed column. As the sample passes through the column, the various components interact with the column material. Each component elutes at a different rate, depending on how strongly it interacts with the column.\u00a0The outlet of the column feeds directly into a detector that characterizes the eluted compounds based on column retention time and signal strength. Eventually, the sample and carrier gas are vented out as waste.<\/p>\n<h2><\/h2>\n<h2>Constant carrier gas flow<\/h2>\n<p>It is critical that the GC outputs accurate, repeatable results to ensure differences between two sample injections are <em>only\u00a0<\/em>due to differences in chemical<\/p>\n<p>composition. It is therefore imperative to keep the flow rate of the carrier gas constant, as deviations disrupt the detection of chemical compounds.<\/p>\n<\/div>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;3_5,2_5&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;3px|||||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<div id=\"eckb-article-content-body\">\n<p>BASIS\u2122 controllers are fast, accurate, and <a href=\"https:\/\/www.alicat.com\/products\/gas-flow\/mass-flow-controller\/small-thermal-mass-flow-controllers\/\">small mass flow controllers<\/a> from Alicat Scientific that are commonly used to deliver exacting inert gas flows. They provide the following benefits to GC applications:<span style=\"font-size: 14px;\">\u00a0<\/span><\/p>\n<ul>\n<li><strong>Stable, low-flow control:<\/strong> Even in low flow conditions, BASIS controllers provide ultra steady control.<\/li>\n<li><strong>Gas compatibility:<\/strong> BASIS can control nine pure gases: air, N2, O2, CH4, He, H2, Ar, CO2, N2O<\/li>\n<li><strong>Easy to integrate &amp; use:<\/strong> Communicate via analog, RS-232, RS-485, or ModbusRTU.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<\/div>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_image src=&#8221;https:\/\/www.alicat.com\/wp-content\/uploads\/2024\/04\/BASIS-Coin_620px.webp&#8221; alt=&#8221;Small mass flow controller BASIS by Alicat Scientific with quarter for comparison. Great performance in a small footprint.&#8221; title_text=&#8221;BASIS_MassFlowController_AlicatScientific&#8221; url=&#8221;@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjQwODA3In19@&#8221; _builder_version=&#8221;4.27.0&#8243; _dynamic_attributes=&#8221;url&#8221; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;3px|||||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_text][et_pb_text _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<h2>Maintaining stable pressure control with fixed orifices<\/h2>\n<p>Gas chromatographs with fixed orifice valves require stable pressure control. A common solution is our <a href=\"https:\/\/www.alicat.com\/products\/pressure\/pressure-controller\/small-pressure-controllers-oem\/\">OEM pressure controller (EPC-Series)<\/a>, <span style=\"color: #000000;\">which provides numerous benefits to GC applications, including:<\/span><\/p>\n<ul>\n<li><span style=\"color: #000000;\"><strong>Compact &amp; easy to integrate:\u00a0<\/strong>These compact controllers are easy to integrate into pre-existing setups, and can be customized to almost any flow rate, pressure condition, or speed required for GC applications.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>High quantity:\u00a0<\/strong>These are a good option for high-volume OEM applications, as they are sold in batches of 25 or more units.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Fast, versatile control:\u00a0<\/strong>An EPC can be configured with either single proportional valves<\/span>, <a href=\"https:\/\/www.alicat.com\/products\/pressure\/pressure-controller\/small-pressure-controllers-oem\/\">dual proportional valves<\/a>, <span style=\"color: #000000;\">or to control back pressure with control response times to 50 ms.<\/span><\/li>\n<\/ul>\n<p>In addition, to use in gas chromatography applications, a single-valve EPC is ideal for regulating straightforward applications such as using a pressure regulator to knock down inlet pressure off a gas bottle, providing volumetric flow control against a calibrated orifice, or controlling stability in any desktop analyzer, lab in a box, reactor, or sample preparer.<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;40%&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|0px||0px|false|false&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_width_all=&#8221;2px&#8221; border_color_all=&#8221;#EAEAEA&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<p><img decoding=\"async\" src=\"https:\/\/www.alicat.com\/wp-content\/uploads\/2024\/04\/EPC-15PSIG-P01_P05-A000_R23-194x300-1.webp\" width=\"194\" height=\"300\" alt=\"Photo of EPC-Series\" class=\"wp-image-39497 alignnone size-full\" style=\"display: block; margin-left: auto; margin-right: auto;\" \/><\/p>\n<p id=\"caption-attachment-34481\" class=\"wp-caption-text\" style=\"text-align: center;\">Single valve electronic pressure controller<\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;40%&#8221; module_alignment=&#8221;center&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; border_width_all=&#8221;1px&#8221; border_color_all=&#8221;#EAEAEA&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<p><img decoding=\"async\" src=\"https:\/\/www.alicat.com\/wp-content\/uploads\/2024\/04\/EPCD-15PSIG-P01_P05-A000_R23-209x300-1.webp\" width=\"209\" height=\"300\" alt=\"Photo of Alicat EPCD-Series dual valve OEM electronic pressure controllers\" class=\"wp-image-39498 alignnone size-full\" style=\"display: block; margin-left: auto; margin-right: auto;\" \/><\/p>\n<p id=\"caption-attachment-34488\" class=\"wp-caption-text\" style=\"text-align: center;\">Dual valve electronic pressure controller<\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.23.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text module_id=&#8221;verify-in-house&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<h1>Verifying gas\u00a0chromatograph\u00a0operation in-house<\/h1>\n<p>The flow rate of the carrier gas in the gas chromatograph is critical to the accurate performance of the instrument. An Alicat<a href=\"https:\/\/www.alicat.com\/products\/pressure\/pressure-meter\/portable-pressure-meters\/\"> portable mass flow meter<\/a> is an accurate and versatile device that is capable of <a href=\"https:\/\/www.alicat.com\/support\/validating-verifying-and-calibrating-flows\/\">verifying<\/a> the performance of a GC, such as the flow rate of the carrier gas. It can be used to check\u00a0mass flow, pressure, and volume measurement on the input and vent of the GC.<\/p>\n<p>These meters offer numerous benefits including:<\/p>\n<ul>\n<li><span style=\"color: #000000;\"><strong>Fast, accurate, &amp; repeatable:\u00a0<\/strong>NIST-traceable accuracy of \u00b10.5% of reading or \u00b10.1% of full scale with &lt;10 ms response times and a repeatability of \u00b1(0.1% of reading + 0.02% of full scale).<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Highly versatile measurement:\u00a0<\/strong>One device can verify both the pressure and flow of 98+ gases across a wide 10,000:1 operating range to cover both capillary and carrier gas flows.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Easy integration into existing setups:\u00a0<\/strong>RS-232 serial communications for data logging to any PC, PDA, or other device with serial terminal capability<\/span><\/li>\n<\/ul>\n<p>The flow rate of the carrier gas in the gas chromatograph is critical to the accurate performance of the instrument. An Alicat<a href=\"https:\/\/www.alicat.com\/products\/gas-flow\/mass-flow-meter\/portable-mass-flow-meters\/\"> portable mass flow meter<\/a> is an accurate and versatile device that is capable of <a href=\"https:\/\/www.alicat.com\/support\/validating-verifying-and-calibrating-flows\/\">verifying<\/a> the performance of a GC, such as the flow rate of the carrier gas. It can be used to check\u00a0mass flow, pressure, and volume measurement on the input and vent of the GC.<\/p>\n<p>These meters offer numerous benefits including:<\/p>\n<ul>\n<li><span style=\"color: #000000;\"><strong>Fast, accurate, &amp; repeatable:\u00a0<\/strong>NIST-traceable accuracy of \u00b10.5% of reading or \u00b10.1% of full scale with &lt;10 ms response times and a repeatability of \u00b1(0.1% of reading + 0.02% of full scale).<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Highly versatile measurement:\u00a0<\/strong>One device can verify both the pressure and flow of 98+ gases across a wide 10,000:1 operating range to cover both capillary and carrier gas flows.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Easy integration into existing setups:\u00a0<\/strong>RS-232 serial communications for data logging to any PC, PDA, or other device with serial terminal capability.<\/span><\/li>\n<\/ul>\n<ul><\/ul>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221; sticky_enabled=&#8221;0&#8243;]<h2><strong>Conclusion<\/strong><\/h2>\nAlicat has been working with customers on gas chromatography applications for over 25 years. <a href=\"https:\/\/www.alicat.com\/contact\/\">Contact our applications engineers<\/a> to find the best GC control or verification solutions for your process.[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"featured_media":46458,"parent":0,"template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"1920","content-type":"","_searchwp_excluded":""},"categories":[],"class_list":["post-38083","support","type-support","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Verifying and Optimizing Gas Chromatography Processes - Alicat Scientific<\/title>\n<meta name=\"description\" content=\"Gas chromatography (GC) is an important analytical technique used to separate and analyze chemical components in a mixture. Here, we provide a brief introduction to GC and discuss some of the common application challenges and mass flow\/pressure solutions.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.alicat.com\/de\/unterstutzung\/uberprufung-und-optimierung-von-gaschromatographieprozessen\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Verifying and Optimizing Gas Chromatography Processes\" \/>\n<meta property=\"og:description\" content=\"Gas chromatography (GC) is an important analytical technique used to separate and analyze chemical components in a mixture. 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Im Folgenden geben wir eine kurze Einf\u00fchrung in die GC und er\u00f6rtern einige der h\u00e4ufigsten Anwendungsprobleme und L\u00f6sungen f\u00fcr Massenfluss und Druck.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.alicat.com\/de\/unterstutzung\/uberprufung-und-optimierung-von-gaschromatographieprozessen\/","og_locale":"de_DE","og_type":"article","og_title":"Verifying and Optimizing Gas Chromatography Processes","og_description":"Gas chromatography (GC) is an important analytical technique used to separate and analyze chemical components in a mixture. 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