[et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”2em||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_heading title=”Compact Gassing Modules Save Space and Simplify Design of Benchtop Bioreactors” _builder_version=”4.27.4″ _module_preset=”default” custom_css_free_form=”selector h1 {|| text-wrap: pretty;||}” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][et_pb_divider color=”#2A3B47″ divider_weight=”2.5px” _builder_version=”4.27.4″ _module_preset=”default” height=”0px” custom_margin=”3rem||3rem||true|false” custom_margin_tablet=”3rem||3rem||true|false” custom_margin_phone=”2rem||2rem||true|false” custom_margin_last_edited=”on|phone” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”0px||0px||true|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_heading title=”Gas Control in Stirred Bioreactors” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”||2rem||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
Gas control is critical for maintaining optimal conditions for cell growth in bioreactors. In most stirred bioreactors, gas is controlled through a combination of sparging (sub\u2011surface) and headspace sweeping (super\u2011surface). Gases such as oxygen and nitrogen assist cell culture growth while removal of carbon dioxide prevents toxic buildup.<\/p>\n
Sparging, the introduction of gases directly into the medium, creates bubbles that dissolve gases into the liquid. Although a theoretically simple process, many variables related to sparging control are essential to optimizing mass transfer. The optimal levels can vary greatly between bioreactors and culture types.<\/p>\n
[\/et_pb_text][et_pb_heading title=”Key Mass Transfer Factors Influenced by Sparging” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”||2rem||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
While sparging is essential for gas introduction, the effectiveness of this process is heavily influenced by the precise control of gas flow rates.<\/p>\n
[\/et_pb_text][et_pb_heading title=”The Role of Flow Control” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”||2rem||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
Flow rates of gas into stirred bioreactors are essential to performance, as they directly impact bubble formation and size. Flow rates must also be carefully controlled, or they will provide excessive turbulence, which will harm the cells. Lower flow rates are advantageous for benchtop bioreactors as they optimize gas distribution by creating small bubbles, without excessive turbulence.<\/p>\n
Traditional gas control systems can be bulky and complex, posing challenges in space\u2011constrained laboratories. Compact mass flow gassing modules offer a solution by providing precise gas control while saving space and simplifying design.<\/p>\n
[\/et_pb_text][et_pb_heading title=”BASIS\u2122 Compact Gassing Modules” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][et_pb_image src=”https:\/\/www.alicat.com\/wp-content\/uploads\/2024\/06\/BasisManifold_coin_600px.webp” alt=”Miniature Gassing Module with BASIS mass flow controllers from Alicat Scientific for OEM applications.” _builder_version=”4.27.4″ _module_preset=”default” max_width=”40%” max_width_tablet=”40%” max_width_phone=”70%” max_width_last_edited=”on|phone” module_alignment=”center” custom_padding=”||2rem|2rem|false|false” custom_padding_tablet=”||2rem|2rem|false|false” custom_padding_phone=”||2rem|0rem|false|false” custom_padding_last_edited=”on|phone” custom_css_main_element=”float: right;” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”float: none;” custom_css_main_element_tablet=”float: right;” theme_builder_area=”post_content”][\/et_pb_image][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”||2rem||false|false” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” sticky_enabled=”0″]Alicat\u00ae<\/sup> Scientific, a leader in flow control technology, has developed custom BASIS gassing modules<\/a> to address specific needs in biotechnology. This streamlined, efficient solution not only simplifies the control of flow rates but also optimizes them, providing highly repetitive and fast gas control. By incorporating a custom\u2011engineered BASIS gassing module, laboratories can improve space efficiency and performance, making it a valuable addition to bioreactor setups.[\/et_pb_text][et_pb_heading title=”Advantages of BASIS Gassing Modules” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h3″ global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” custom_margin=”||2rem||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n Compact gassing modules offer a streamlined, efficient solution for gas control in bioreactors. By simplifying engineering and saving space, these gassing modules enhance bioreactor performance and productivity, making them invaluable tools for the biotech industry.<\/p>\n Contact<\/a> Alicat Scientific to explore how BASIS<\/a> can transform your operations.<\/p>\n\n